Instrument for Formulation Development
Instrument for Formulation Development

Instrument for Formulation Development

At our company, we are equipped with a comprehensive suite of advanced instruments designed to support research, development, and scale-up of diverse dosage forms. Our instruments integrate both classical pharmaceutical equipment and state-of-the-art analytical and processing systems. This combination enables seamless transition from early-stage laboratory experiments to pilot-scale and industrial production, ensuring robust and reproducible results across all development stages. These instruments also allow our scientists to precisely control critical quality attributes such as particle size, dissolution rate, bioavailability, stability, and homogeneity.

The Core Instrumentation Suite

Mixing and Blending Instruments

  • V-Blenders and Bin Blenders: Widely used for solid dosage forms.
  • High-Shear Mixers: Ideal for creating uniform wet masses and dispersing fine powders.
  • Magnetic and Overhead Stirring Systems: Used in liquid formulations.

Particle Size Reduction and Engineering Equipment

  • Jet Mills: Use compressed air to reduce particle size without heat generation.
  • Ball Mills: Used for fine grinding and solid-state blending.
  • High-Pressure Homogenizers: Reduce droplet or particle size in emulsions and suspensions.

Emulsification and Dispersion Instruments

  • Ultrasonic Homogenizers: Generate high-energy cavitation to produce nano- and micro-emulsions.
  • Rotor-Stator Systems: Provide efficient dispersion of immiscible phases.
  • Membrane Emulsification Units: Allow controlled droplet formation with narrow size distribution.

Solid Dosage Processing Equipment

  • Wet Mixing Granulator: Enables uniform granule formation with controlled moisture addition.
  • Dry Granulator: Suitable for moisture-sensitive APIs.
  • Rotary Tablet Press: High-speed compression system ensuring consistent tablet weight, hardness, and thickness.
  • Coating Machine: Used for film coating, enteric coating, and modified-release layering.
  • Laser Punching Machine: Enables precision-controlled tablet or film modification for controlled-release systems.

Encapsulation & Softgel Tools

  • Roll Mode Softgel Machine: Used for efficient production of soft gelatin capsules with uniform fill and sealing integrity.
  • Cylinder-Type Soft Capsule Encapsulating Machine: Provides high-precision encapsulation for oils, suspensions, and poorly soluble drugs.

Hot Melt and Novel Delivery Tools

  • Thermo Hot Melt Extruder: Enables solid dispersion systems for poorly soluble APIs.
  • Spray Drying System: Produces amorphous solid dispersions and inhalable particles with controlled particle size distribution.

Semi-Solid and Transdermal Development Equipment

  • Laser-Beam Drilling Machine: Used to create controlled pores in transdermal systems.
  • Transdermal Permeation Analyzer: Evaluates skin permeation kinetics and enhances formulation optimization for patches and gels.
  • Automatic Suppository Filling Machine: Ensures precise dosing and uniformity in rectal and vaginal dosage forms.

Analytical and Quality Control Instruments

  • Centrifuges for solid-liquid separation
  • Ultra HPLC / HPLC / GC Systems
  • Dissolution Apparatus (Dual Speed, Dual Media)
  • Flow Cell Systems (Open Loop & Closed Loop)
  • Reciprocating Holder/Cylinder Analyzer
  • Particle Size Analyzers
  • Rheometers
  • DSC Instruments
  • ...

Types of Formulations We Develop

With our advanced instrumentation, we are capable of developing a wide range of pharmaceutical dosage forms, including:

  • Solid Dosage Forms: Tablets, capsules, and powders with controlled release or immediate release properties.
  • Liquid Formulations: Solutions, suspensions, and syrups designed for oral or parenteral administration.
  • Semi-Solid Preparations: Creams, gels, and ointments for topical delivery.
  • Injectable Formulations: Sterile solutions, emulsions, and lyophilized products for intravenous or intramuscular use.
  • Advanced Drug Delivery Systems: Nanoformulations, liposomes, microspheres, and sustained-release systems.

By combining advanced processing technologies, high-precision analytical systems, and versatile formulation capabilities, we are able to design and develop a wide spectrum of pharmaceutical formulations.

Please kindly note that our services are for research use only.

Get in Touch

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