| Hygroscopicity Evaluation |
| Hygroscopicity evaluation is the process of evaluating the hygroscopic performance of APIs and excipients under different humidity conditions. Our company can determine the hygroscopicity of APIs and excipients in different humidity environments through experiments, and help customers determine the formulation of preparations, storage conditions of drugs, etc. |
| Thermal Analysis |
| Thermal analysis is the study of the properties and stability of substances by measuring their thermal properties at different temperatures. Our company can use thermal gravimetric analysis (TGA), differential scanning calorimetry (DSC), and other techniques to test the thermal properties of APIs to determine important information such as thermal decomposition characteristics and thermal stability. |
| Solubility Detection |
| The solubility of a drug is an important factor affecting its absorption and bioavailability. Our company can evaluate the solubility and dissolution rate of APIs through in vitro test methods to support drug formulation. |
| Determination of Partition Coefficients |
| The partition coefficient describes the degree of APIs distribution in different phases (usually the oil phase and water phase), which has an important impact on drug distribution and metabolism in the body. Our company can help customers understand the in vivo behavior of APIs by determining the partition coefficient with appropriate methods. |
| Determination of pKa |
| The pKa value of APIs is an important parameter to describe its dissociation properties under different pH conditions. Our company can choose an appropriate method to determine the pKa value according to the properties of APIs and provide data support for pharmaceutical formulations. |
| API-Excipient Compatibility |
| During formulation development, drug-excipient interactions may affect its stability and efficacy. Our company can evaluate the compatibility between raw materials and excipients through various testing methods to help customers choose suitable formulations. |
| Particle Size Distribution |
| Particle size distribution refers to the percentage or number of different particle sizes present in a sample. This is critical for drug bioavailability, potency, stability, and uniformity during formulation. Our company can measure and analyze the particle size distribution of drugs in preformulation through modern particle size analysis technology, helping customers understand the size range and distribution of particles in formulation. |
| Particle Size Reduction |
| During the formulation process, the particle size of the drug may need to be adjusted to meet specific formulation requirements or to improve the bioavailability of the drug. Our company can develop appropriate methods and processes to reduce the particle size according to the customer's needs and the characteristics of the formulation. |
