Sotagliflozin

Name: Sotagliflozin
SKU: PI1018899041
Rating: 5 (1 reviews)

Catalog NumberPI1018899041

CAS Number1018899-04-1

CategoryAntidiabetics

Sotagliflozin is an S-glycosyl compound that is 1-thio-beta-L-xylopyranose in which the anomeric hydroxy group is replaced by a 4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl group and the thiol is replaced by a methylsulfanediyl group. It is an inhibitor of SGLT1 and SGLT2 that is approved to reduce the risk of cardiovascular death, hospitalization for heart failure, and urgent heart failure visit in adults with heart failure or type 2 diabetes mellitus, chronic kidney disease, and other cardiovascular risk.

Product Details

Synonyms	LX-4211
Molecular Formula	C21H25ClO5S
Molecular Weight	424.9
Key Use	Anti-hyperglycemic

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Other Identifiers

IUPAC Name	(2S,3R,4R,5S,6R)-2-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-6-methylsulfanyloxane-3,4,5-triol
InChI	InChI=1S/C21H25ClO5S/c1-3-26-15-7-4-12(5-8-15)10-14-11-13(6-9-16(14)22)20-18(24)17(23)19(25)21(27-20)28-2/h4-9,11,17-21,23-25H,3,10H2,1-2H3/t17-,18-,19+,20+,21-/m1/s1
InChI Key	QKDRXGFQVGOQKS-CRSSMBPESA-N
Canonical SMILES	CCOC1=CC=C(C=C1)CC2=C(C=CC(=C2)[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)SC)O)O)O)Cl
EC Number	805-113-6
MDL Number	MFCD22493506

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