Roxadustat

Name: Roxadustat
SKU: PI808118403
Rating: 5 (1 reviews)

Catalog NumberPI808118403

CAS Number808118-40-3

CategoryAntianemics

Roxadustat is a first-in-class hypoxia-inducible factor prolyl hydroxylase inhibitor used to treat anemia associated with chronic kidney disease. It works by reducing the breakdown of the hypoxia-inducible factor (HIF), which is a transcription factor that stimulates red blood cell production in response to low oxygen levels.

Product Details

Synonyms	FG-4592
Molecular Formula	C19H16N2O5
Molecular Weight	352.3
Key Use	Anti-anaemia

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Other Identifiers

IUPAC Name	2-[(4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carbonyl)amino]acetic acid
InChI	InChI=1S/C19H16N2O5/c1-11-15-9-13(26-12-5-3-2-4-6-12)7-8-14(15)18(24)17(21-11)19(25)20-10-16(22)23/h2-9,24H,10H2,1H3,(H,20,25)(H,22,23)
InChI Key	YOZBGTLTNGAVFU-UHFFFAOYSA-N
Canonical SMILES	CC1=C2C=C(C=CC2=C(C(=N1)C(=O)NCC(=O)O)O)OC3=CC=CC=C3
EC Number	813-400-2
MDL Number	MFCD20040519

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