Magnesium Sulphate

Magnesium Sulphate

Cat. No.: PI10034998

Magnesium Sulphate
Product Details
CAS 10034-99-8
Molecular Formula H14MgO11S
Molecular Weight 246.47
Standard BP / EP / IP / USP
Uses (1) Treatment of severe toxemias (pre-eclampsia) of pregnancy and acute nephritis in children.
(2) Magnesium sulfate injection is indicated for replacement therapy in magnesium deficiency, especially in acute hypomagnesemia accompanied by signs of tetany similar to those of hypocalcemia.
(3) In animals indicated for tetany treatment and uterine tetany as a myometrial relaxant.
Mechanism Of Action Magnesium sulfate reduces striated muscle contractions and blocks peripheral neuromuscular transmission by reducing acetylcholine release at the myoneural junction. Additionally, Magnesium inhibits Ca2+ influx through dihydropyridine-sensitive, voltage-dependent channels. This accounts for much of its relaxant action on vascular smooth muscle.

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