Filgotinib Maleate

Name: Filgotinib Maleate
SKU: PI1802998759
Rating: 5 (1 reviews)

Catalog NumberPI1802998759

CAS Number1802998-75-9

CategoryRheumatology

Filgotinib Maleate is the maleate form of filgotinib, an orally bioavailable inhibitor of the tyrosine kinase Janus kinase 1 (JAK1), with potential anti-inflammatory and immunomodulating activities.

Product Details

Synonyms	Cyclopropanecarboxamide, N-(5-(4-((1,1-dioxido-4-thiomorpholinyl)methyl)phenyl)(1,2,4)triazolo(1,5-a)pyridin-2-yl)-, (2Z)-2-butenedioate (1:1)
Molecular Formula	C25H27N5O7S
Molecular Weight	541.6
Key Use	Anti-rheumatoid arthritis

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Other Identifiers

IUPAC Name	(Z)-but-2-enedioic acid;N-[5-[4-[(1,1-dioxo-1,4-thiazinan-4-yl)methyl]phenyl]-[1,2,4]triazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide
InChI	InChI=1S/C21H23N5O3S.C4H4O4/c27-20(17-8-9-17)23-21-22-19-3-1-2-18(26(19)24-21)16-6-4-15(5-7-16)14-25-10-12-30(28,29)13-11-25;5-3(6)1-2-4(7)8/h1-7,17H,8-14H2,(H,23,24,27);1-2H,(H,5,6)(H,7,8)/b;2-1-
InChI Key	BFENHEAPFWQJFL-BTJKTKAUSA-N
SMILES	C1CC1C(=O)NC2=NN3C(=N2)C=CC=C3C4=CC=C(C=C4)CN5CCS(=O)(=O)CC5.C(=C\C(=O)O)\C(=O)O
EC Number	848-707-0

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