Dorzolamide HCl

Name: Dorzolamide HCl
SKU: PI130693822
Rating: 5 (1 reviews)

Catalog NumberPI130693822

CAS Number130693-82-2

CategoryOphthalmic Agents

Dorzolamide (dorzolamide hydrochloride) is a topical carbonic anhydrase (CA) inhibitor used to lower intraocular pressure (IOP) by reducing aqueous humour formation. It is formulated as a 2% eye drop for use in the management of glaucoma and ocular hypertension.

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Project Description

Molecular Formula	C10H17ClN2O4S3
Molecular Weight	360.9
Available Formulations	Opthalmic
Technology	Synthetic
CEP/DMF/GMP	Canada DMF, CEP, EU DMF, US DMF
Mechanism Of Action	It works by blocking an enzyme in the ciliary process that regulates ion balance and fluid pressure in the eyes. Unlike oral CA inhibitors, dorzolamide has negligible effects of acid-base or electrolyte disturbances and other systemic adverse effects.