Carbimazole

Catalog NumberPI22232548

CAS Number22232-54-8

CategoryEndocrinology & Metabolism

Carbimazole is an anti-thyroid agent that decreases the uptake and concentration of inorganic iodine by thyroid; it also reduces the formation of di-iodotyrosine and thyroxine. Once converted to its active form of methimazole, it prevents the thyroid peroxidase enzyme from coupling and iodinating the tyrosine residues on thyroglobulin, hence reducing the production of the thyroid hormones T3 and T4.