Abiraterone Acetate

Catalog NumberPI154229182

CAS Number154229-18-2

CategoryAntineoplastic Agents

Abiraterone Acetate is used for treatment of metastatic castrate-resistant prostate cancer. It is an orally active acetate salt of the steroidal compound abiraterone with antiandrogen activity. Abiraterone inhibits the enzymatic activity of steroid 17alpha-monooxygenase (17alpha-hydrolase/C17,20 lyase complex), a member of the cytochrome p450 family that catalyzes the 17alpha-hydroxylation of steroid intermediates involved in testosterone synthesis. Administration of this agent may suppress testosterone production by both the testes and the adrenals to castrate-range levels.